Muhammad Tufail*

Tufal. J Clin Transl Res 2023; 9(4):22.00195

Published online: July 12, 2023


Background and aim: There are two significant challenges in cancer treatment: malignancy and resistance to anti-cancer drugs. As a result, a thorough understanding of cancer etiology is essential for developing new cancer treatments. There is a crucial role for micro-RNAs in physiological processes as well as pathological processes. Cancer pathogenesis is strongly influenced by miRNAs, which play a crucial role in neoplastic disease pathophysiology. They can be used to diagnose, prognosticate, and treat a wide range of cancers. Also, they play an important role in metastasis and resistance to treatment and the stamens of cancer stem cells by regulating several signaling networks. A better understanding of the miRNAs that play a role in cancer's signaling pathways could lead to new cancer diagnostic, prognostic, and treatment options. This study focuses on miRNAs, which play a vital part in regulating cancer-related signaling networks and pathogenic signaling pathways in cancer.
Relevance for patients: This study highlights the relevance of microRNAs (miRNAs) in cancer, as they have a significant role in cancer development, metastasis, treatment resistance, and cancer stem cells. Understanding the role of miRNAs in cancer signaling pathways could lead to improved diagnostics, prognostics, and treatment options for patients.



Author affiliation

Institute of Biomedical Sciences, Shanxi University, Taiyuan 030006, China

*Corresponding author
Muhammad Tufail
Institute of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.
Tel: +86 130 3348 0817

Handling editor:
Michal Heger
Department of Pharmaceutics, Utrecht University, the Netherlands
Department of Chemistry, Utrecht University, Utrecht, the Netherlands
Department of Pathology, Erasmus Medical Center, the Netherlands
Department of Pharmaceutics, Jiaxing University Medical College, Zhejiang, China


Epub ahead of print (1.6 MB)